A paper co-authored with Dr. Tomoya Shintani (Toyo Institute of Food Technology, Kawanishi, Hyogo)*has been published in KAGAKU TO SEIBUTSU (Journal of Japan Society for Bioscience, Biotechnology, and Agrochemistry).
This review presents the Interventions Testing Program (ITP), mainly carried out by the U.S. National Institute on Aging. Over the past 20 years, about 50 compounds or drugs have been tested for their lifespan-extending effects using mice. Among these, several compounds, including Rapamycin, have been reported to increase lifespan. These compounds have potential for use in controlling aging and related diseases in mammals, including humans.
* Tomoya Shintani, Isao Shimokawa: Effects of Food and Drug Ingredients on Life Span in Genetically Heterozygous Mice- Verification of anti-aging effects using hybrid mice at multiple facilities. KAGAKU TO SEIBUTSU, 63 (10): 446-448, 2025.